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Footnotes:

1. Zippin, J.H., Farrell, J., Huron, D., Kamenetsky, M., Hess, K.C., Fischman, D.A., Levin, L.R., and Buck, J. (2004). Bicarbonate responsive 'soluble' adenylyl cyclase defines a nuclear cAMP microdomain. J. Cell. Biol. 164:527-534.

2. Sun, X. C., Cui, M. & Bonanno, J. A. [HCO3-]-regulated expression and activity of soluble adenylyl cyclase in corneal endothelial and Calu-3 cells. BMC Physiol 4, 8 (2004).

3. Wang, Y. et al. Regulation of CFTR channels by HCO3--sensitive soluble adenylyl cyclase in human airway epithelial cells. Am J Physiol Cell Physiol 289, C1145-1151 (2005).

4. Baudouin-Legros, M. et al. Control of basal CFTR gene expression by bicarbonate-sensitive adenylyl cyclase in human pulmonary cells. Cell Physiol Biochem 21, 075-086 (2008).