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About Us


Corporate Officers

David A. Zippin, M.B.A., J.D.
President & Chief Executive Officer


Our Expert Scientific Advisors

Jochen Buck, M.D., PhD

Dr. Buck has been studying intracellular cAMP signaling pathways for the last 14 years. He received his MD and PhD from the University of Tubingen (Germany). As a Post-doctoral Fellow in the laboratory of Dr. Ulrich Hammerling at Sloan-Kettering Cancer Center, he studied intracellular signaling by vitamin A, and he continued these studies during his first years as a faculty member of the Pharmacology Department of Weill Cornell Medical College. Starting in 1998, he collaborated with Dr. Lonny Levin to identify, clone, and biochemically characterize a novel form of adenylyl cyclase in mammals, the soluble adenylyl cyclase (sAC). He and Dr. Levin remain collaborators studying the biochemistry and biology of mammalian sAC. They have combined their laboratories into a joint research program studying bicarbonate/carbon dioxide chemosensing via the second messenger cAMP. 


Publications


Chen*, Y., M.J. Cann*, T.N. Litvin, V. Iourgenko, M.L. Sinclair, L.R. Levin, and J. Buck (2000). Soluble adenylyl cyclase as an evolutionarily conserved bicarbonate sensor. Science 289: 625-628. PMID: 10915626


Hess, K.C.*, Jones, B.H.*, Marquez, B., Chen, Y., Ord, T.S., Kamenetsky, M., Myamoto, C., Zippin, J.H., Kopf, G.S., Suarez, S.S., Levin, L.R.*, Williams, C.J.*, Buck, J.*, & Moss, S.B.* (2005). The “soluble” adenylyl cyclase in sperm mediates multiple signaling events required for fertiliztion. Dev. Cell 9: 249-259. PMID: 16054031


Tresguerres, M., Levin, L.R., and Buck, J. (2011) Intracellular cAMP signaling by soluble adenylyl cyclase. Kidney Int. 79: 1277-1288.

PMID: 21490586





Lonny Levin, PhD

Dr. Levin has been studying the cAMP signaling pathway for over 20 years and adenylyl cyclases for over 15. As a Graduate Student in the Laboratory of Dr. Mark J. Zoller at Cold Spring Harbor Laboratory, he used molecular genetics and biochemistry to study the regulation of Protein Kinase A, the predominant cAMP effector protein in cells. As a Post-doctoral Fellow in the laboratory of Dr. Randall R. Reed at Johns Hopkins School of Medicine, he cloned and characterized the first Drosophila adenylyl cyclase. As a member of the Pharmacology Department of Weill Cornell Medical College, he first continued his studies identifying and characterizing Drosophila adenylyl cyclase genes. Then in 1998, he collaborated with Dr. Buck to identify, clone, and biochemically characterize a novel form of adenylyl cyclase in mammals, the soluble adenylyl cyclase (sAC). He and Dr. Buck remain collaborators studying the biochemistry and biology of mammalian sAC. They have combined their laboratories into a combined research program studying bicarbonate/carbon dioxide chemosensing via the second messenger cAMP.

Publications


Buck*, J., M.L. Sinclair*, L. Schapal, M.J. Cann, and L.R. Levin (1999). Cytosolic adenylyl cyclase defines a unique signaling molecule in mammals. Proc. Natl. Acad. Sci. 96:79-84. PMID: 9874775


Tresguerres, M. Buck, J. and Levin, L.R. (2010). Physiological carbon dioxide, bicarbonate and pH sensing. Pflugers Archiv - European Journal of Physiology 460:953-964. PMID: 20683624


Lee, Y-S., Tresguerres, M., Hess, K., Marmorstein, L.Y., Levin, L.R., Buck, J., and Marmorstein, A.D. (2011). Regulation of anterior chamber drainage by bicarbonate sensitive adenylyl cyclase in the ciliary body. J. Biol. Chem:jbc.M111.284679. doi:10.1074/jbc.M111.284679. PMID: 21994938





Jonathan H. Zippin, M.D., PhD

Jonathan Hale Zippin M.D., Ph.D. is an Attending Dermatologist and Instructor in Dermatology at Weill Medical College of Cornell. Dr. Zippin attended Cornell University where he received a Bachelor of Science with Honors. He then attended the Rockefeller/Cornell/Sloan-Kettering Tri-Institutional MD/PhD program. He then completed his general medicine internship at the Mount Sinai Hospital in New York City, followed by a residency in dermatology at the Weill Cornell Medical Center - New York Presbyterian Hospital.  Dr. Zippin is a member of the American Academy of Dermatology, the American Society of Dermatologic Surgery, and the American Contact Dermatitis Society. He is also a member of the medical editorial board of the Journal of Drugs in Dermatology.  Dr. Zippin is the author of numerous peer-reviewed publications in the area of signal transduction and skin disease, and has published a variety of papers reviewing the treatment of dermatologic diseases.

Publications



In the News




Cynthia Magro, M.D.


Dr. Cynthia Magro is professor of pathology and laboratory medicine and director of the comprehensive dermatopathology service at the Weill College of Medicine of Cornell University located in upper east side of Manhattan. Dr. Magro received her training at Harvard Medical School. She is internationally known in dermatopathology, having co-authored over 200 papers, several book chapters, and three textbooks: the Melanocytic Proliferation, the Cutaneous Lymphoid proliferation, and Cutaneous Biopsy Interpretation.  She is a co-editor on the Barnhill Textbook of Dermatopathology. Her expertise has focused on the pathologic assessment of cutaneous autoimmune disease, viral disease, immunofluorescence, drug reactions, benign, atypical an neoplastic lymphocytic infiltrates of the skin, and problematic melanocytic proliferations. In addition she has expertise in the area of non-neoplastic lung disease where she has functioned as the senior author on several papers in the areas of pulmonary vasculitis, idiopathic pulmonary fibrosis and lung transplantation. She has also developed a novel approach to the evaluation of non-neoplastic inflammatory lung disease via direct immunofluorescent techniques, which has been published in the new 2008 book Pulmonary Pathology (Churchill Liningstone). She currently runs the non-neoplastic lung service at the Weill College of Medicine and New York Hospital. Dr. Cynthia Magro has been recognized as a New York Times, Super Doctor in 2008, 2009, and 2010. She has also been listed in the Castle Connolly Medical Limited as a Top Doctor for the New York Metro Area in 2010 and 2011. She is a member of the American Society of Dermatopathology and United States and Canadian Academy of Pathologists.


Publications